Laboratory Diagnosis of Novel Coronavirus Disease 2019 (COVID-19) Infection
DOI:
https://doi.org/10.36570/jduhs.2020.2.998Abstract
A cluster of pneumonia cases were reported to World Health Organization (WHO) on 31st December, 2019 from the city of Wuhan, China which were later identified to be caused by a novel coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The outbreak spread globally and on 11th March 2020, WHO declared COVID-19 as a pandemic. There have been continuous efforts to optimize methods to screen and diagnose large proportion of coronavirus affected population. COVID-19 diagnostic approaches include real-time reverse transcription-PCR (RT-PCR) and serological diagnosis.
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Chan JF, Yip CC, To KK, Tang TH, Wong SC, Leung KH, et al. Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens. J Clin Microbiol. 2020;58(5):e00310-20. doi:10.1128/JCM.00310-20
Russo A, Minichini C, Starace M, Astorri R, Calò F, Coppola N. Current Status of Laboratory Diagnosis for COVID-19: A Narrative Review. Infect Drug Resist. 2020;13:2657-2665. Published 2020 Aug 3. doi:10.2147/IDR.S264020
Tang YW, Schmitz JE, Persing DH, Stratton CW. Laboratory Diagnosis of COVID-19: Current Issues and Challenges. J Clin Microbiol. 2020;58(6):e00512-20. doi:10.1128/JCM.00512-20
Li X, Geng M, Peng Y, Meng L, Lu S. Molecular immune pathogenesis and diagnosis of COVID-19. J Pharm Anal. 2020;10(2):102-108. doi:10.1016/j.jpha.2020.03.001
Hong KH, Lee SW, Kim TS, Huh HJ, Lee J, Kim SY, et al. Guidelines for laboratory diagnosis of coronavirus disease 2019 (COVID-19) in Korea. Ann Lab Med. 2020 Sep 1;40(5):351-60. doi:10.3343/alm.2020.40.5.351
Tahamtan A, Ardebili A. Real-time RT-PCR in COVID-19 detection: issues affecting the results.
Gao Y, Li T, Han M, Li X, Wu D, Xu Y, et al. Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19. J Med Virol. 2020;92(7):791-796. doi:10.1002/jmv.25770
National Institute of Health (NIH). COVID – 19 Laboratory Capacity in Pakistan.
The Nation. Pakistan's testing capacity for COVID-19 is over 16,000 per day: WHO. Available at: https://nation.com.pk/09-May-2020/pakistan-s-testing-capacity-for-covid-19-is-over-16-000-per-day-who Accessed: 25th August 2020
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Copyright (c) 2020 Muddasir Saqib
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Articles published in the Journal of Dow University of Health Sciences are distributed under the terms of the Creative Commons Attribution Non-Commercial License https://creativecommons.org/ licenses/by-nc/4.0/. This license permits use, distribution and reproduction in any medium; provided the original work is properly cited and initial publication in this journal. 
